The Gut–CBS Connection: Why Your SIBO Protocol May Be Missing the Mark

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As health practitioners, we’re trained to spot the signs of SIBO: bloating, gas, abdominal pain, inconsistent stools, and food sensitivities. And often, we reach for our tried-and-tested protocols — antimicrobial herbs, probiotics, motility agents, and dietary adjustments like low FODMAP. But what happens when your patient’s SIBO keeps returning? When they’ve tried “everything” — and still feel worse after sauerkraut, juicing, or high-sulphur foods?

The answer may lie upstream — in a misunderstood yet critical metabolic pathway: the CBS (cystathionine beta-synthase) pathway.

What Is the CBS Pathway and Why It Matters

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