Neurotransmitters 101 — Understanding the Five Key Classes and Their Clinical Relevance

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Neurotransmitters are fundamental to how our patients think, feel, sleep, move, and cope with stress. While most clinicians are familiar with serotonin and dopamine, a deeper understanding of all neurotransmitter classes—and how genetic, nutritional, and inflammatory factors modulate them—is essential for functional and integrative practice.

This blog introduces the five main classes of neurotransmitters, how they function, and what clinical signs can alert us to imbalance—especially in the context of genetic susceptibility (e.g. COMT, MAO, MTHFR, HNMT, DHFR).

The Five Classes of Neurotransmitters

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