October 23, 2025

How Mould Disrupts Biochemistry, Immunity & Detoxification Understanding the systemic impact of mycotoxins in clinical practice Mould-related illness is often misunderstood as a localised respiratory issue, but in reality, mycotoxins disrupt the body at nearly every level. From mitochondrial damage to immune dysregulation and impaired detoxification, their effects are complex, far-reaching, and deeply biochemical. For […]

How polymorphisms in sulfur and antioxidant pathways may increase mitochondrial stress and taurine demand Introduction Mitochondrial dysfunction is a core feature of many chronic conditions seen in clinical practice—ranging from cardiovascular disease and neurodegeneration to diabetes, chronic fatigue, and neurodevelopmental disorders. At the cellular level, it manifests as impaired ATP production, increased oxidative stress, calcium

As health practitioners, we’re trained to spot the signs of SIBO: bloating, gas, abdominal pain, inconsistent stools, and food sensitivities. And often, we reach for our tried-and-tested protocols — antimicrobial herbs, probiotics, motility agents, and dietary adjustments like low FODMAP. But what happens when your patient’s SIBO keeps returning? When they’ve tried “everything” — and

Neurotransmitters are fundamental to how our patients think, feel, sleep, move, and cope with stress. While most clinicians are familiar with serotonin and dopamine, a deeper understanding of all neurotransmitter classes—and how genetic, nutritional, and inflammatory factors modulate them—is essential for functional and integrative practice. This blog introduces the five main classes of neurotransmitters, how

Key points discussed: How Vitamin B12 is Absorbed, Transported & Utilised What is Transcobalamin II (TCN2) genes The Role of Genetic Variants in B12 Metabolism Signs & Symptoms of TCN2 Polymorphisms Lab Tests Every Functional Health Practitioner Should Use Diseases & Conditions Linked to TCN2 SNPs  

Nutritional Clues in Recurrent Vaginitis During Pregnancy: What Practitioners Need to Know Recurrent vaginitis during pregnancy remains a challenging clinical concern with potential implications for both maternal and fetal health. While the standard approach focuses on microbiological and symptomatic assessment, emerging evidence suggests a pivotal, yet underexplored, dimension: nutrition. A recent study by Çıkım and

My Top Tips For Explaining Complex Genomic Information To Patients As a practitioner, explaining complex genomic information to patients can be a challenge. While the science is intricate, your role is to translate these insights into actionable, patient-friendly guidance. Effective communication ensures patients understand their results and feel empowered to take charge of their health.

To avoid overwhelm, start with these key SNPs and pathways: MTHFR (C677T, A1298C), MTR, TCN2: Affects folate metabolism and methylation.

How Genes Interact with Diet, Lifestyle, and the Environment: A Functional Approach The genetic code is often referred to as the blueprint for the body, but it’s not a static destiny. Instead, genes interact dynamically with diet, lifestyle, and environmental factors, shaping how that blueprint is expressed. This interaction provides opportunities to optimise health outcomes

Legal implications that practitioners should be aware of when working with genetic information include: Privacy and Confidentiality: Practitioners must comply with data privacy laws, such as GDPR in Europe, HIPAA in the U.S., or the Australian Privacy Principles, which require secure handling, storage, and sharing of genetic information. Genetic data is considered sensitive information, so